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Several physicians also reported prescribing GLP-1RAs for additional off-label uses, including chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and idiopathic intracranial hypertension

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It works by blocking the reabsorption of glucose in the kidneys, causing excess glucose to be excreted in the urine

It also appears to exert a protective effect on the gut-brain axis, reducing symptoms of anxiety and stress-induced damage through modulation of serotonin and dopamine systems

The sermorelin and tirzepatide stack refers to the combined use of two distinct peptide medications: sermorelin, a growth hormone-releasing hormone analogue, and tirzepatide (Mounjaro), an MHRA-licensed dual GIP/GLP-1 receptor agonist for type 2 diabetes and weight management

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