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These technological advancements may significantly improve the pharmacological profile of antioxidant agents and enhance their therapeutic potential in future clinical applications

Of these BDNF has received considerable attention regarding depression and stress [58] and AD [55,59,60]

Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats

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When administered the peptide, mice with moderate AD exhibited a reduced level of amyloid beta plaques in the brain, improved cognitive functionality and synaptic transmission, and protection against neuronal death