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Fat loss patterns Visceral fat, the metabolically dangerous fat surrounding internal organs, decreases proportionally more than subcutaneous fat during semaglutide treatment

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Serious Safety Considerations Although uncommon, important risks exist

Planning dose increases around less socially demanding periods can help manage the adjustment period

Surprisingly, the SURMOUNT-5 trial found that fewer people discontinued tirzepatide due to side effects (2.7%) compared to semaglutide (5.6%)