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Description

Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]

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Specific antibodies may aid in detecting malignant cells on the biopsy, such as immunostaining of MITF (microphthalmia-associated transcription factor) [4]

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