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This drug and dosing regimen has demonstrated efficacy in non-human primates after high-dose radiation therapy (Farese 2012) and, as of this writing, Extimia is being evaluated in an open-label randomized phase II clinical study (BCD-017-2), which is expected to conclude in 2013 (ClinicalTrials.gov 2012a)

doi: 10.1016/S1081-1206(10)60492-9

It is important to understand that while tirzepatide significantly reduces appetite in most patients, it does not eliminate hunger entirely

However, the likelihood of this depends on both the amount of folic acid consumed and an individuals genetic capacity to metabolise it

Regular reassessment helps determine appropriate therapy intensity and duration at each life stage