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COAs provide technical information for compliance verification and regulatory reporting

Mitochondrial dysfunction within atrial myocytes plays a crucial role in driving electrical and structural remodeling processes

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In some instances, conventionally used methods of sterilization (e.g., heat treatment (e.g., in an autoclave), gamma irradiation, filtration) lead to irreversible degradation of polymeric components (e.g., thermosetting, gelling or mucoadhesive polymer components) and/or the active agent in the formulation