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ISRCTN Registry, ResearchGate 2 Glucose control & metabolic markers in type 2 diabetes / pre-diabetes 14 g/day for 852 weeks 2024 dose-response meta-analysis of 36 RCTs (n=3 214) found clinically meaningful reductions in fasting glucose (9 mg/dL), HbA1c (0.32 %) and HOMA-IR (0.43)

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[DOI] [PubMed] [Google Scholar] 22.Abu-Freha N., Yitzhak A., Shirin H., Nevo-Shor A., Abu-Jaffar J., Abu-Rafe S., Afianish Y., Cohen D.L., Bermont A

353,354 For instance, protecting Schwann cells from glucose-induced toxicity improves nerve function and promotes remyelination in experimental models

Aroda, M.D., from Brigham and Women's Hospital in Boston, and colleagues randomly assigned adults with type 2 diabetes inadequately controlled with diet and exercise to receive once-weekly subcutaneous cagrilintide 2.4 mg plus semaglutide 2.4 mg, cagrilintide 1.0 mg plus semaglutide 1.0 mg, or placebo for 40 weeks (62, 63, and 64 participants, respectively)