It is not approved by the FDA or EMA for human use
HDN-derived NETs can promote the retention of LDNs in the liver, preventing their clearance by macrophages
As acetaminophen detoxification proceeds in this fashion, glutathione, a ubiquitous cellular antioxidant, eventually becomes depleted (Moyer 2011), and NAPQI can no longer be sufficiently detoxified (James 2003)
Patients with chronic exposure to toxins, such as heavy metals or pollutants, could potentially find relief as glutathione aids in the neutralization and elimination of these substances
[DOI] [PMC free article] [PubMed] [Google Scholar] Mapstone M., Lin F., Nalls M.A., Cheema A.K., Singleton A.B., Fiandaca M.S., Federoff H.J
Gene 67 , 3140 (1988)