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The majority of the studies reviewed, including studies reporting genotype frequencies among individuals without cancer, had a case-control design

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Patel points out that while the production of free radicals is an inescapable aspect of our biology that promotes aging, we might be able to influence the pace of aging by quenching free radicals more effectively with antioxidants like GSH

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Similarly, intracellular excess iron can overwhelm ferritin storage capacity, increasing the size of the labile iron pool (LIP), a pool of loosely bound, redox-active iron within the cell [96]

In addition, they have identified many additional genes that are protective and aim to further explore these to see if there are any additional therapeutic possibilities suggested by their research