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If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization

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Song F, Eastwood AJ, Gilbody S, et al

The protective effect of SFN appears to be NRF2-dependent, as NRF2 deficiency exacerbated psoriasis-like symptoms, as well as the inflammatory response and abnormal proliferation of keratinocytes in the mice, and SFN had little therapeutic effect in the IMQ-modeled knockout mice

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Alberts JF, Engelbrecht Y, Steyn PS, Holzapfel WH, van Zyl WH (2006) Biological degradation of aflatoxin B1 by Rhodococcus erythropolis cultures