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[1] [2] Weight management formulations are contraindicated during pregnancy

Shmerling, MD Senior Faculty Editor, Harvard Health Publishing

Repeated administration of 50% of the LD 50 (i.e., 40 mg/kg body weight per day for 10 - 21 days), caused myelin pallor and micro-vacuolation of the white matter

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Thus, the clinically therapeutic strategy for T2DM should not only effectively control the patients glucose levels, but also minimize the complications of bone metabolism diseases

Moreau, R., Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion