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Fentanyl has the most favorable metabolic profile, but is less practical for the outpatient setting, as the lowest available transdermal patch dose may still be too high for patients with significant hepatic impairment [16]

Curr Opin Gastroenterol 2017

Clinical trials show semaglutide produces 1522% body weight reduction over 68 weeks at therapeutic doses

Clinical, Cosmetic and Investigational Dermatology , 10 , 147-153

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