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Changes to diet and exercise are advised along with the medication

By blocking prostaglandin synthesis, naproxen reduces inflammatory responses and provides analgesia

Handling, Storage and Documentation From an operational viewpoint, Cagrilintide is handled like other lyophilised peptide vials: Store sealed vials at 28 C in a dry, dark environment

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Reference: Hsieh et al., 2017 (VEGFR2AkteNOS signalling involvement) VEGFR2 activation triggers: VEGF binding VEGFR2 autophosphorylation (turns on VEGFR2) which leads to PI3K activation which leads to Akt phosphorylation Akt (Protein Kinase B) is critical because it phosphorylates (turns on) eNOS which leads to Nitric oxide synthesis more nitric oxide

& Bernet, V