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Magnetic resonance imaging studies of patients included in a Phase 1B/2A clinical trial showed slowing of the rate of decline in hippocampal volume in the treated group and evidence of increased hippocampal volume in APOE4 gene carriers

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This includes the upregulation of genes encoding acetyl-CoA carboxylase alpha (ACACA), elongase of very long chain FAs 1 (Elovl1), Elovl5, Elovl6, fatty acid synthase (FASN) , and stearoyl-CoA desaturase 2 (SCD2)

Using the same spot repeatedly can cause skin irritation, bumps, or even changes in how the medication works

Ingredients per capsule: acetyl-L-carnitine hydrochloride (70.8%) - of which acetyl-L-carnitine 510 mg, capsule shell (gelatin), cellulose (filler), magnesium stearate, silicon dioxide (anti-caking agents)