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New ways in which GLP-1 can regulate glucose homeostasis Text PDF Abstract Glucagon-like peptide1 (GLP-1) has a diverse set of peripheral actions which all serve to promote enhanced glucose tolerance, and for this reason it has become the basis for new treatments for type 2 diabetes

Blood Pressure and Lipids Both medications produce similar improvements in cardiovascular risk factors: Blood pressure: Both typically reduce systolic BP by 3-6 mmHg Effects are similar between medications Lipids: Both reduce triglycerides Modest effects on LDL cholesterol Similar lipid improvements Metabolic Comparison Cost and Insurance Cost considerations may influence medication choice for some patients

MOTS-c has emerging preclinical + early clinical

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Most patients inject in the abdomen or thigh using a small insulin-type needle

Mounjaro is not for people with type 1 diabetes or children