Earlier GHRPs GHRP-2 and GHRP-6, the two peptides ipamorelin replaced in most compounding protocols, both trigger cortisol and, to varying degrees, prolactin release via off-target receptor binding
For a patient with untreated Cushings disease or on high-dose glucocorticoid therapy, an elevated serum IGF-I may be observed, but levels decrease following remission or cessation of glucocorticoid therapy, respectively
Conclusion Sourcing and Regulatory Considerations The main lesson in ipamorelin dosage is simple
Appl Microbiol Biotechnol 107 , 45434551 (2023)
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Schedule Once daily in research planning, due to the 20-30 hour half-life