This event eventually leads to accumulation of ROS in the cell that results in disturbance in redox steadiness, which could trigger harm to vital cell components such as proteins, lipids, and DNA, and potentially elevate the risk of somatic mutations and neoplastic transformation [8, 13]
* Results may vary
However, distinct biochemical pathways are actively turned-on during inflammation in the resolution phase (67), providing evidence for the role of active biochemical pathways in resolution and possibilities for new therapeutic targets
The supernatant from the hypotonic solution was combined with the supernatant from the hypertonic solution, centrifuged to remove debris, and dialyzed against 20LmM Tris, pH 7.5 and 150LmM NaCl (Tris-buffered saline, TBS) overnight at 4 C
Gut 1991;32(10):1151-5
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