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Most events were reported as mild-to-moderate and concentrated during dose escalation

However, real-world data from the Cleveland Clinic found that a substantial share of patients maintained meaningful loss at one year, largely through restarting or transitioning treatment

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In practice, people losing weight on GLP-1s rely on the drug to create and maintain a calorie deficit

Teleanu DM, Niculescu AG, Lungu II et al

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