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10.1016/0196-9781(93)90071-n 103 SardiniaM

What the Research Suggests Clinical studies and pilot trials evaluating intralesional PRP for Peyronies disease have demonstrated: Favorable safety profiles Potential improvements in curvature and sexual function Reduced plaque density in some patients Some investigational protocols specifically include plaque needling prior to PRP injection , recognizing that mechanical disruption may enhance the effectiveness of regenerative therapies

Common side effects, such as nausea, vomiting, and gastrointestinal disturbances, can lead to patient non-compliance or early discontinuation of therapy

Consider supplementation when the patient has risk factors associated with B 12 Deficiency as described in see Table 1: Patient Risk Factors Associated with B 12 Deficiency above

Carrie Decker, ND , graduated with honors from the National University of Natural Medicine in Portland, OR

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