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[DOI] [PubMed] [Google Scholar] 114.Grinberg L., Fibach E., Amer J., Atlas D

Global disruption of Gclm results in mice (GCLM knockout) that have 15% of hepatic GSH levels seen in wild-type mice 16

Together, these findings identify the melatonin-NRF2-glutathione axis as a metabolic checkpoint regulating innate type 2 immunity and suggest that therapeutic targeting of redox metabolism may represent a strategy for modulating airway inflammation in allergic asthma

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Exp Neurobiol 2015

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