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The relevance of these findings to humans has not been determined

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However, people with significant weight-loss resistance often have blunted GLP-1 responses that lifestyle changes alone cannot fully overcome

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However, the use of anticholinergic drugs, such as tiotropium bromide in chronic models of asthma, reduces M3 expression in bronchia, the Th2 profile, and airway hyperresponsiveness (AHR) (Kang et al., 2012

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