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Researchers use specialised imaging software to quantify the number of branch points and tube length

This leads researchers to assume that there is a heritable component to mastocytosis as well (e.g., other genes involved).[ref][ref] In addition to KIT mutations, systemic mastocytosis also has links to mutations in the JAK2, PDGFR, NRAS, RASGRP4, CBL, IL4, TET2, and IL13 genes.[ref] MicroRNAs are also involved in the regulation of KIT expression.[ref] Interestingly, about half of all kids with cutaneous mastocytosis tend to outgrow it and go into long-term remission

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Researchers originally developed it because they noticed that this particular region of growth hormone seemed responsible for its fat-metabolizing properties, without the growth-promoting or blood sugar effects that make full-length growth hormone problematic for weight management