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After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

The MAD portion of the study (cohorts 68) included 24 participants with overweight or obesity who were otherwise healthy (18 who received CT-388 and six in the pooled placebo group)

Mitochondrial fission and fusion are governed by a balance between pro-fission proteins (such as DRP1, Fis1, and MFF) and pro-fusion proteins (such as MFN1, MFN2, OPA1, MIEF1, and MIEF2), with DRP1 standing out as the key regulator of mitochondrial fission [42]

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Diclofenac sdico 75 mg: hidroxicobalamina 10 mg