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When a week feels like nothing is happening, the rest of the timeline often shows what actually changed even if the scale did not move that week

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95% CI, 0.43-0.75)

An emphatic increase in the expression of two markers of mucin levels, MUC2 and MUC5 genes, was observed after metformin treatment (Kyriachenko et al., 2019)

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However, surgery is unlikely to be a feasible population-level solution, due to the nature of complications, limited healthcare capacity and acceptability