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This impairs iron efflux from pulmonary macrophages, resulting in intracellular iron accumulation (165)

Teleanu DM, Niculescu A, Lungu II, Radu CI, Vladcenco O, Roza E, et al

XPO1 inhibition targets transcriptional vulnerability of FLT3-ITD+835D double mutant AML through p53 accumulation and inhibition of oncogenic transcription factors: lesson learned from CAGE sequencing of primary AML cells

It circulates through your system, identifying and neutralizing free radicalsunstable molecules that can damage cells if left unchecked

doi: 10.1016/j.cell.2022.06.003 19 JiangYLiuXSunM

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