Sermorelin is a synthetic peptide that stimulates the release of growth hormone from the pituitary gland
New clinical guidelines from the American College of Physicians (ACP) recommend semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) as first-line medications for adults with obesity
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These medications also improve insulin response and glucose control, which also supports weight loss
The finding that older participants 45 were more likely to report no change in nicotine cravings (53.3%) may suggest that the behavioral effects of GLP-1 agonists are less pronounced in older populations, possibly due to age-related neurochemical changes or lower GLP-1 receptor sensitivity
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