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These endogenous peptides play critical roles in glucose homeostasis and metabolic regulation

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It also showed that lymphatic-specific inhibition of mitochondrial complex III (a component of the electron transport chain that plays an important role in cellular metabolism) suppresses metastasis and enhances the response to immunotherapy in preclinical models

When it was first approved by the FDA under the brand name Geref , it was indicated for children with idiopathic growth hormone deficiency who had a functioning pituitary gland

(2024) Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models