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One research participant described the medications primary benefit as turning off her food noise. When that effect ends, former users may face the return of cravings and persistent thoughts about their next meal

However, these studies are observational, not randomized trials, so we cannot yet interpret the findings as proof of a cancer risk reduction. The review also addressed the question of whether GLP-1s reduce cancer risk because they cause weight loss and improved metabolism, or because they have a direct anti-cancer effect