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Worobey M, Han GZ, Rambaut A

A critical note for anyone treating melasma: heat is one of the most significant melasma triggers

Target tissues include those that are most affected by the disease (heart, kidney, brain, smooth muscle and endothelial cells) or those that can act as a production factory of the enzyme, such as the liver

There also is a cohort of so-called Spitzoid tumors of uncertain malignant potential or STUMP lesions whose name reflects the challenge in diagnosis [47]

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PIEZO1, a mechanosensitive ion channel, has been found to be an important regulator of IR-induced ferroptosis in pulmonary endothelial cells [71]