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Researchers have also discovered a compound, ferroptosis-inducer-56 (FIN56), that can degrade GPX4 and deplete coenzyme Q10 (CoQ10) via the mevalonate pathway, thus initiating ferroptosis ( via chaperone-mediated autophagy is another approach to induce ferroptosis ( Figure 1 )

10.12998/wjcc.v12.i21.470 39 ZhangW.LiuM.JiY.YuD.MaC.ZhaoJ.et al (2023)

doi: 10.1186/s12934-018-1037-1 78 SunaS.YamaguchiF.KimuraS.TokudaM.JitsunariF

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