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IGF-1 plays a critical role in skeletal muscle growth during development, muscle regeneration and muscle hypertrophy in response to training

This pattern developed from several considerations

Researchers have identified mutations in multiple genes that seem to increase susceptibility, along with familial patterns indicating a hereditary component

Goal: Explore anabolic and metabolic effects driven by sustained IGF-1 receptor activity from this long-acting analog effects studied preclinically and not established in humans [1] [2]

Furthermore, tremendous evidences have reported its anticancer, anti-hypertension, anti-liver injury and improving immune response effects (Jing et al

Lane 1: human HepG2 whole cell lysates, Lane 2: human A549 whole cell lysates, Lane 3: human MOLT-4 whole cell lysates, Lane 4: human RT4 whole cell lysates, Lane 5: human Daudi whole cell lysates, Lane 6: human K562 whole cell lysates, Lane 7: rat kidney tissue lysates, Lane 8: mouse kidney tissue lysates, Lane 9: mouse colon tissue lysates