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doi: 10.1161/HYPERTENSIONAHA.117.07802

Primary carnitine deficiency is a genetic disorder of the cellular carnitine delivery system that typically manifests around the age of five with symptoms of cardiomyopathy, skeletal muscle weakness and hypoglycemia

Owaki, R., Aoki, H., Toriuchi, K., Inoue, Y., Hayashi, H., Takeshita, S., et al

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J.FeldmanE

Specifically, lactylation of Tufm at K286 impedes its interaction with Tomm40 on mitochondria, thereby inhibiting the mitochondrial localization of Tufm and Tufm-mediated mitophagy in injured neurons