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(4) Simulation Results and Projected Impact to MIPS Eligible Clinicians Based on the methodology described in the preceding sections we created a baseline and proposed policies simulation

Since nicotine is a weak base (pKa=8.0), at a higher pH, a larger portion of nicotine is unprotonated (free-base) and nicotine is more volatile.62 Because of higher pH, a significant proportion of nicotine is present in the gas phase of inhaled aerosol