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There have been studies that have shown that nicotine is capable of altering the signal system of the brain mainly in the dopaminergic, cholinergic, and glutamatergic neurotransmitter systems, they explain

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In that survey, ninth- and 10th-graders who reported using nicotine were more likely to use flavored non-tobacco oral nicotine products -- gummies, tablets, lozenges and gums -- than many more traditional products like cigarettes