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7,16,48 Under realistic e-cigarette use conditions, sucralose degrades to give hydrochloric acid that either reacts with propylene glycol or glycerol to produce chloropropanols and other chlorinated compounds, or enhances the degradation of propylene glycol and glycerol to produce toxic aldehydes and hemiacetals (formaldehyde-releasing agents)

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So, is nicotine a stimulant, a depressant, or both