This has sparked curiosity around nicotine, niacin, and how isolated biochemical mechanisms can sometimes be misunderstood - blurring the line between correlation and causation
From a harm-reduction standpoint, nicotine patches are often considered one of the cleaner options because they avoid combustion, inhalation, flavorings, and many oral additives
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Triggers can be varied and change over time
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Chronic exposure to nicotine through smoking disrupts the functional connectivity between the NBM and precuneus in MCI patients (Qiu et al., 2022)
