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In conditions such as asthma and COPD, mitochondrial dysfunction leads to increased mtROS production, which activates the NLRP3 inflammasome

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As such, mitochondrial phagocytosis might downregulate excessive inflammation and serve as a protective mechanism in patients with COPD (Yao et al., 2021)

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More than 5 million Americans age 40 and older have diabetic retinopathy due to type 1 or type 2 diabetes