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Caffeine is extracted over time, and so the first 30 seconds of a five minute steeping cycle may only extract 20 to 30% of the caffeine (the amount depends on the leaf and processing style)

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As the gums continue to pull back, the exposed root surfaces become highly vulnerable to decay and infection

doi: 10.1038/s41590-019-0568-x 18 TravesSLCulpittSVRussellREKBarnesPJDonnellyLE

A bidirectional association has been observed between smoking and several psychiatric disorders, such as bipolar disorder 36 , schizophrenia 43 and anxiety 44 in observational studies