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CDV is usually transmitted through the air, but it can also be transmitted through physical contact with saliva, urine, feces, and even human hands

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It may also be a sign that an outbreak is about to start.

Invading microorganisms can be sensed through specific pathogen-associated molecular patterns recognized by pathogen recognition receptors on DCs, such as Toll-like receptors (TLRs), C-type lectin receptors, cytosolic Nod-like receptors, and rig-like receptors

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