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The new EU tobacco products directive went into effect May 2016, meaning that all tobacco packaging and hand-rolled cigarette containers must include large and graphic pictorial health warnings, which will cover 65% of the packaging, with additional warning messages on every packet

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However, misconceptions about their safety, social acceptability, and long-term health effects persist among university students

Estimates of the geometric mean serum cotinine concentration and its 95% CI are plotted for each of 3 time periods (1988-1991, 1999-2004, and 2011-2012), along with the best-fitting trend line

Second, the results of the study are product specific under acute laboratory condition of use and cannot be extended to other HTPs or to the same products under investigation after prolonged use

[28] Redevelopment [edit] In 2004, the previously abandoned American Tobacco Campus (ATC) in Durham was reopened as a complex of offices, shops, and restaurants